Enjoy modern amenities, clean comfort, and superior service at our hotel in Santa Maria, CA Situated along Hwy 101 between Santa Barbara and San Luis Obispo in sunny Santa Maria, California, the hotel embodies the area's casual charm and is the perfect home base for visitors to the area. Holiday Inn & Suites Santa Maria is minutes to local wineries along The Foxen Canyon Wine Trail, enjoy the fresh local produce, take a dip in the Pacific Ocean in nearby Pismo Beach, see a race at Santa Maria Speedway, or head to one of the nearby recreation areas like Guadalupe-Nipomo Dunes. Holiday Inn & Suites Santa Maria is ideally located for visitors to the area on business. Vandenberg Space Force Base, Lockheed Martin, Boeing, and agricultural industries are all just a short drive away. Plus, the Holiday Inn & Suites Santa Maria offers spacious rooms and suites equipped with all the creature comforts of home. We are the perfect location for a quick trip or an extended stay. All our spacious guest rooms feature a mini refrigerator and microwave. You can stay productive while on the road with our free high-speed Wi-Fi, blow off some steam in our Fitness Center before taking a relaxing dip in our outdoor heated pool and spa, or savor a delicious meal at the Portabella Bar & Grill.